Toxic encephalopathy due to colchicine--Gloriosa superba poisoning.

Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning.

Colchicine cardiotoxicity following ingestion of Gloriosa superba tubers.

The clinical features of colchicine toxicity in a patient following ingestion of Gloriosa superba tubers are described. Gastroenteritis, acute renal failure, cardiotoxicity and haematological abnormalities were the main toxic manifestations. There was no hypotension and no neurological manifestations. Electrocardiographic changes were noteworthy and have not been reported previously.

Quantification of Colchicine in Seed and Tuber samples of Gloriosa superba by High Performance Liquid Chromatography method

To quantify the colchicine (alkaloid) present in Gloriosa superba by High Performance Liquid Chromatography (HPLC) method. Gloriosa superba species are known for their content of colchicine, a valuable alkaloid in the seeds and tubers (corms). HPLC analysis was carried out to confirm the presence of colchicine in Gloriosa superba. Treatment of gibberellic acid and Psedomonas aerugenosa improved...

Improved growth and colchicine concentration in Gloriosa superba on mycorrhizal inoculation supplemented with phosphorus-fertilizer.

BACKGROUND Gloriosa superba produces an array of alkaloids including colchicine, a compound of interest in the treatment of various diseases. The tuber of Gloriosa superba is a rich source of colchicine which has shown anti-gout, anti-inflammatory, and anti-tumor activity. However, this promising compound remains expensive and Gloriosa superba is such a good source in global scale. Increase in ...

Optimization of extraction conditions for colchicine from Gloriosa superba tubers using response surface methodology

Gloriosa superba is a medicinal plant used in traditional medicine for the treatment of various diseases. The tuber of Gloriosa superba is a rich source of colchicine which is used for the treatment of gout, cirrhosis and also used in plant breeding studies to produce polyploidy. Optimization of various extraction parameters using response surface methodology (RSM) was performed to assess maxim...